产品货号：
Z17649
中文名称：
GGCX抗体
英文名称：
Anti-GGCX Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-GGCX Antibody |
| 指标别名 | gamma glutamyl carboxylase;GC;GGCX;VKCFD1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | WB,IHC,ICC/IF,FCM,ELISA |
| 基因名称 | GGCX |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human GGCX recombinant protein (Position:M75-A730). |
| 实际分子量 | 88KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Gamma-glutamyl carboxylase is an enzyme that in humans is encoded by the GGCX gene,located on chromosome 2 at 2p12.This gene encodes an integral membrane protein of the rough endoplasmic reticulum that carboxylates glutamate residues of vitamin K-dependent proteins to gamma carboxyl glutamate,a modification that is required for their activity.The vitamin K-dependent protein substrates have a propeptide that binds the enzyme,with carbon dioxide,dioxide,and reduced vitamin K acting as co-substrates.Vitamin K-dependent proteins affect a number of physiologic processes including blood coagulation,prevention of vascular calcification,and inflammation.Allelic variants of this gene have been associated with pseudoxanthoma elasticum-like disorder with associated multiple coagulation factor deficiency.Alternative splicing results in multiple transcript variants. |
| Uniprot ID | P38435 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | gamma-glutamyl carboxylase |
| 蛋白名全称 | Vitamin K-dependent gamma-carboxylase |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells Enzyme linked immunosorbent assay (ELISA) 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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